|Can Juan Pierre replace Manny? Well, no.
Believe it or not, that's the one aspect of this story that we can get a pretty firm handle on immediately.
Ramirez has hit .380 with a .490 on-base percentage, .710 slugging percentage, 23 homers, and 73 RBIs in 80 games since joining the Dodgers last season.
Obviously keeping up that type of torrid pace is extremely difficult, but if we assume for a moment that Ramirez would have continued to hit like that during the 50 games he'll be suspended it would have been worth 25-30 runs more than a replacement-level hitter.
The "replacement-level hitter" tag is important, because Ramirez's primary fill-in is expected to be Juan Pierre and his .291/.332/.345 line in 1,168 plate appearances since joining the Dodgers two years ago is almost exactly replacement level. In other words, if the Dodgers were to give all 50 of Ramirez's missed starts to Pierre it would cost them 25-30 runs offensively (assuming both players hit like they have so far in Los Angeles).
Of course, while the move from Ramirez to Pierre is a massive downgrade offensively it's also likely a sizable upgrade defensively. My conservative estimate is that the difference between Ramirez and Pierre in left field for 50 games would be worth at least five runs, which takes a chunk out of the runs lost offensively. Add it all up and losing Ramirez for 50 games while replacing him with Pierre figures to cost the Dodgers around 20 runs.
Throughout baseball history 10 runs gained or lost has generally been worth one win, which means Ramirez's suspension projects to knock two wins off the Dodgers' total. That may not seem like a tremendous amount, but they won the division by exactly two games last season and that's a six- or seven-win pace over the course of an entire season.
Fortunately for the Dodgers they've already built up a 6.5-game lead over the Giants and an 8.5-game lead over the Diamondbacks, Rockies, and Padres in an NL West division filled with some very flawed teams. Arizona, Colorado, San Francisco, and San Diego have combined for a 48-60 (.444) record thus far after winning 82, 74, 72, and 63 games respectively last season.
Ramirez made a huge impact in 53 games with the Dodgers last season and has been the driving force behind their MLB-best 21-8 start this season, but the rest of the team is strong enough and the rest of the division is weak enough that there's a very good chance Los Angeles will still be holding a multiple-game lead when he returns on July 3.